Neuroscientist Sergiu P. Pasca has made it his life’s work to understand how the human brain builds itself — and what makes it susceptible to disease. In a mind-blowing talk laden with breakthrough science, he shows how his team figured out how to grow what they call brain “assembloids” — self-organizing clumps of neural tissue derived from stem cells that have shown the ability to form circuits — and explains how these miniature parts of the nervous system are bringing us closer to demystifying the brain.